Summary
Check out the National Institute for Health Research website for more opportunities.
The latest research opportunities from the National Institute for Health Research North West Regional Research Delivery Network (RRDN) are as follows:
- DaRE2THINK – is an individual-patient, randomised, parallel-group, open-label, event-driven superiority trial with 1:1 allocation to either direct oral anticoagulant (DOAC) or no added therapy. A staged internal pilot programme is incorporated into the design of this Clinical Trial of an Investigational Medicinal Product (CTIMP). It will test the hypothesis that DOACs are effective at reducing thromboembolic events and vascular dementia compared to no treatment, in patients with AF and a low or intermediate expected risk of stroke. Using a healthcare data approach to reduce the burden on both NHS staff and patients. (NB – this study is open to practices who are registered with CPRD).
- ANTLER75+ – is recruiting adults aged 75 years or over who have been taking an antidepressant but are now well enough to stop (depression improved). The trial aims to see if it is better to continue on the antidepressant for a further 12 months or to taper off and discontinue to prevent a relapse.
- EXTOD-Active – The effect of interrupting sitting with regular active breaks on glycaemia and daily insulin dose in sedentary people with type 1 diabetes. Participants will complete pre- randomisation baseline procedures before allocation to four weeks of habitual activity (control) or active breaks. Interstitial glucose concentrations (fGM), insulin dose and physical activity/ postural transitions (ActivPAL) will be monitored throughout. To improve generalisability and feasibility of recruiting the required number of participants, the study will be completed in a free-living environment using remote data collection methods.
All research studies are available to browse on the NIHR Primary Care Research Hub.
The NIHR has also partnered with organisations on the following studies:
- GP Lunch & Learn Series With the Care Responders Study – The Care Responders study is looking at how first responders can better help young people experiencing a mental health crisis.
- Understanding the Wellbeing and Support Needs of Partners of Parents with Bipolar (PPB Study) – This study is sponsored by the University of Lancaster and aims to get a clearer understanding of the well-being and support needs of partners of parents with Bipolar disorder. Practices are being asked to display a poster in their patient waiting rooms to advertise the study.
More information about clinical research and the work of the NIHR NW RRDN can be found on the PCB website.
